Burgundy-Franche-Comté represents 4% of the national economy and demographics. A region with an industrial and agricultural tradition, it has been on a path of slow growth since the 2000s. Like the entire national territory, population and employment are distributed unevenly in the region, forming four major groups. On the Rhine-Rhône axis from Chalon-sur-Saône to Belfort, the urban network is multipolar but tight, favoring the interdependence of territories and exchanges, and thereby network operation. In the rest of the territory, the urban network is looser, with a few large employment centers that are more autonomous or more oriented towards outside the region: Sens, Auxerre, Nevers, Mâcon. The eastern part of the region has a very specific profile, due to the attractiveness of the very close Swiss employment centers. Finally, a large part of the west of the region, very sparsely populated, is faced with issues linked to “hyper-rurality”: geographical isolation, aging of the population, low financial resources, lack of equipment and services...